The D-amino acid peptide D3 reduces amyloid fibril boosted HIV-1 infectivity

BACKGROUND: Amyloid fibrils such as Semen-Derived Enhancer of Viral Infection (SEVI) or amyloid-β-peptide (Aβ) enhance HIV-1 attachment and entry. Inhibitors destroying or converting those fibrils into non-amyloidogenic aggregates effectively reduce viral infectivity. Thus, they seem to be suitable...

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Autors principals: Widera, Marek, Klein, Antonia Nicole, Cinar, Yeliz, Funke, Susanne Aileen, Willbold, Dieter, Schaal, Heiner
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899924/
https://ncbi.nlm.nih.gov/pubmed/24422713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-11-1
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