Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

Microglia are crucial for the pathogenesis of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). Here, we show that the E3 ubiquitin ligase Peli1 is abundantly expressed in microglia and serves as a pivotal mediator of microglial activation during the course of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Xiao, Yichuan, Jin, Jin, Chang, Mikyoung, Chang, Jae-Hoon, Hu, Hongbo, Zhou, Xiaofei, Brittain, George C., Stansberg, Christine, Torkildsen, Øivind, Wang, Xiaodong, Brink, Robert, Cheng, Xuhong, Sun, Shao-Cong
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899792/
https://ncbi.nlm.nih.gov/pubmed/23603814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3111
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados