Tumour-site-dependent expression profile of angiogenic factors in tumour-associated stroma of primary colorectal cancer and metastases

BACKGROUND: Tumour-associated stroma has a critical role in tumour proliferation. Our aim was to determine a specific protein expression profile of stromal angiogenic cytokines and matrix metalloproteinases (MMPs) to identify potential biomarkers or new therapy targets. METHODS: Frozen tissue of pri...

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Detalhes bibliográficos
Main Authors: Kahlert, C, Pecqueux, M, Halama, N, Dienemann, H, Muley, T, Pfannschmidt, J, Lasitschka, F, Klupp, F, Schmidt, T, Rahbari, N, Reissfelder, C, Kunz, C, Benner, A, Falk, C, Weitz, J, Koch, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899771/
https://ncbi.nlm.nih.gov/pubmed/24292449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.745
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