A model of hematopoietic stem cell proliferation under the influence of a chemotherapeutic agent in combination with a hematopoietic inducing agent

BACKGROUND: Hematopoiesis is a complex process that encompasses both pro-mitotic and anti-mitotic stimuli. Pharmacological agents used in chemotherapy have a prominent anti-mitotic effect. The approach of inhibiting cell proliferation is rational with respect to the rapidly dividing malignant cells....

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Main Authors: Mouser, Christina L, Antoniou, Eliana S, Tadros, James, Vassiliou, Evros K
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899742/
https://ncbi.nlm.nih.gov/pubmed/24438084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-11-4
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