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Id3 and Id2 act as a dual safety mechanism in regulating the development and population size of innate-like γδ T cells

The innate-like T cells expressing Vγ1.1 and Vδ6.3 represent a unique T cell lineage sharing features with both the γδ T and the invariant NKT cells. The population size of Vγ1.1(+)Vδ6.3(+) T cells is tightly controlled and usually contributes to a very small proportion of thymic output, but the und...

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Autori principali: Zhang, Baojun, Lin, Yen-Yu, Dai, Meifang, Zhuang, Yuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899720/
https://ncbi.nlm.nih.gov/pubmed/24379125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302694
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