High throughput flow cytometry screening reveals a novel role for JAM-A as a cancer stem cell maintenance factor

Stem cells reside in niches that regulate the balance between self-renewal and differentiation. The identity of a stem cell is linked with the ability to interact with its niche through adhesion mechanisms. To identify targets that disrupt cancer stem cell (CSC) adhesion, we performed a flow cytomet...

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Detalhes bibliográficos
Main Authors: Lathia, Justin D., Li, Meizhang, Sinyuk, Maksim, Alvarado, Alvaro G., Flavahan, William A., Stoltz, Kevin, Rosager, Ann Mari, Hale, James, Hitomi, Masahiro, Gallagher, Joseph, Wu, Qiulian, Martin, Jody, Vidal, Jason G., Nakano, Ichiro, Dahlrot, Rikke H., Hansen, Steinbjørn, McLendon, Roger E., Sloan, Andrew E., Bao, Shideng, Hjelmeland, Anita B., Carson, Christian T., Naik, Ulhas P., Kristensen, Bjarne, Rich, Jeremy N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899718/
https://ncbi.nlm.nih.gov/pubmed/24373972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.11.043
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