Chemical synthesis of a gene for human epidermal growth factor urogastrone and its expression in yeast.

We have chemically synthesized and expressed in yeast a gene coding for human epidermal growth factor (urogastrone), a 53-amino-acid polypeptide that has been shown to promote epithelial cell proliferation and to inhibit gastric acid secretion. The synthetic gene, consisting of 170 base pairs, was d...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Urdea, M S, Merryweather, J P, Mullenbach, G T, Coit, D, Heberlein, U, Valenzuela, P, Barr, P J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1983
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6369317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.24.7461
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