Chemical synthesis of a gene for human epidermal growth factor urogastrone and its expression in yeast.

We have chemically synthesized and expressed in yeast a gene coding for human epidermal growth factor (urogastrone), a 53-amino-acid polypeptide that has been shown to promote epithelial cell proliferation and to inhibit gastric acid secretion. The synthetic gene, consisting of 170 base pairs, was d...

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Bibliografiske detaljer
Main Authors: Urdea, M S, Merryweather, J P, Mullenbach, G T, Coit, D, Heberlein, U, Valenzuela, P, Barr, P J
Format: Artigo
Sprog:Inglês
Udgivet: 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC389971/
https://ncbi.nlm.nih.gov/pubmed/6369317
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