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Polygenic risk and the development and course of asthma: Evidence from a 4-decade longitudinal study

BACKGROUND: Genome-wide association studies (GWAS) have discovered loci that predispose to asthma. To integrate these new discoveries with emerging models of asthma pathobiology, research is needed to test how genetic discoveries relate to developmental and biological characteristics of asthma. METH...

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Detalhes bibliográficos
Main Authors: Belsky, DW, Sears, MR, Hancox, RJ, Harrington, HL, Houts, R, Moffitt, TE, Sugden, K, Williams, B, Poulton, R, Caspi, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899706/
https://ncbi.nlm.nih.gov/pubmed/24429243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-2600(13)70101-2
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