Effect of i.p. insulin administration on IGF1 and IGFBP1 in type 1 diabetes

In type 1 diabetes mellitus (T1DM), low concentrations of IGF1 and high concentrations of IGF-binding protein 1 (IGFBP1) have been reported. It has been suggested that these abnormalities in the GH–IGF1 axis are due to low insulin concentrations in the portal vein. We hypothesized that the i.p. rout...

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Detalhes bibliográficos
Main Authors: van Dijk, P R, Logtenberg, S J J, Groenier, K H, Kleefstra, N, Bilo, H J G, Arnqvist, H J
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899582/
https://ncbi.nlm.nih.gov/pubmed/24327601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-13-0089
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