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Environmental enrichment strengthens corticocortical interactions and reduces amyloid-β oligomers in aged mice

Brain aging is characterized by global changes which are thought to underlie age-related cognitive decline. These include variations in brain activity and the progressive increase in the concentration of soluble amyloid-β (Aβ) oligomers, directly impairing synaptic function and plasticity even in th...

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Detalhes bibliográficos
Main Authors: Mainardi, Marco, Di Garbo, Angelo, Caleo, Matteo, Berardi, Nicoletta, Sale, Alessandro, Maffei, Lamberto
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899529/
https://ncbi.nlm.nih.gov/pubmed/24478697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00001
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