The therapeutic target of estrogen receptor-alpha36 in estrogen-dependent tumors

Estrogen receptor-alpha36 (ER-α36) is a new isoform of estrogen receptors without transcriptional activation domains of the classical ER-α(ER − α66). ER-α36 is mainly located in cytoplasm and plasma membrane. ER-α36 mediates non-genomic signaling and is involved in genomic signaling of other ERs. Re...

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Bibliografiske detaljer
Main Authors: Gu, Yu, Chen, Tianxiang, López, Elena, Wu, Weizhu, Wang, Xiangdong, Cao, Jiang, Teng, Lisong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899443/
https://ncbi.nlm.nih.gov/pubmed/24447535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-16
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