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Visualizing Vpr-Induced G2 Arrest and Apoptosis

Vpr is an accessory protein of human immunodeficiency virus type 1 (HIV-1) with multiple functions. The induction of G2 arrest by Vpr plays a particularly important role in efficient viral replication because the transcriptional activity of the HIV-1 long terminal repeat is most active in G2 phase....

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Bibliografiske detaljer
Main Authors: Murakami, Tomoyuki, Aida, Yoko
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899331/
https://ncbi.nlm.nih.gov/pubmed/24466265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086840
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