Targeting antitumor CD4 helper T cells with universal tumor-reactive helper peptides derived from telomerase for cancer vaccine

Current cancer immunotherapies predominantly rely on CD8(+) T cells to fight against tumors. However accumulative evidence showed that proinflammatory CD4(+) helper T cells are critical determinants of effective antitumor immunity. The utilization of universal tumor-reactive helper peptides from tel...

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Autores principales: Adotévi, Olivier, Dosset, Magalie, Galaine, Jeanne, Beziaud, Laurent, Godet, Yann, Borg, Christophe
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
Materias:
Commentary
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899142/
https://ncbi.nlm.nih.gov/pubmed/23357860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.23587
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