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Alternative splicing of agrin regulates its binding to heparin alpha-dystroglycan, and the cell surface.

Agrin is a basal lamina molecule that directs key events in postsynaptic differentiation, most notably the aggregation of acetylcholine receptors (AChRs) on the muscle cell surface. Agrin's AChR clustering activity is regulated by alternative mRNA splicing. Agrin splice forms having inserts at two s...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: O'Toole, J J, Deyst, K A, Bowe, M A, Nastuk, M A, McKechnie, B A, Fallon, J R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38991/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8693000/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7369
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