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Molecular nonlinear dynamics and protein thermal uncertainty quantification
This work introduces molecular nonlinear dynamics (MND) as a new approach for describing protein folding and aggregation. By using a mode system, we show that the MND of disordered proteins is chaotic while that of folded proteins exhibits intrinsically low dimensional manifolds (ILDMs). The stabili...
Uloženo v:
| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
AIP Publishing LLC
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3899061/ https://ncbi.nlm.nih.gov/pubmed/24697365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4861202 |
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