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Molecular nonlinear dynamics and protein thermal uncertainty quantification
This work introduces molecular nonlinear dynamics (MND) as a new approach for describing protein folding and aggregation. By using a mode system, we show that the MND of disordered proteins is chaotic while that of folded proteins exhibits intrinsically low dimensional manifolds (ILDMs). The stabili...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
AIP Publishing LLC
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3899061/ https://ncbi.nlm.nih.gov/pubmed/24697365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4861202 |
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