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Molecular nonlinear dynamics and protein thermal uncertainty quantification

This work introduces molecular nonlinear dynamics (MND) as a new approach for describing protein folding and aggregation. By using a mode system, we show that the MND of disordered proteins is chaotic while that of folded proteins exhibits intrinsically low dimensional manifolds (ILDMs). The stabili...

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Sonraí Bibleagrafaíochta
Main Authors: Xia, Kelin, Wei, Guo-Wei
Formáid: Artigo
Teanga:Inglês
Foilsithe: AIP Publishing LLC 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899061/
https://ncbi.nlm.nih.gov/pubmed/24697365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4861202
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