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Influence of Aggregation and Route of Injection on the Biodistribution of Mouse Serum Albumin
Protein aggregates are a major risk factor for immunogenicity. Until now most studies on aggregate-driven immunogenicity have focused on linking physicochemical features of the aggregates to the formation of anti-drug antibodies. Lacking is however, basic knowledge on the effect of aggregation on th...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898957/ https://ncbi.nlm.nih.gov/pubmed/24465523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085281 |
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