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PPL2 Translesion Polymerase Is Essential for the Completion of Chromosomal DNA Replication in the African Trypanosome

Faithful copying of the genome is essential for life. In eukaryotes, a single archaeo-eukaryotic primase (AEP), DNA primase, is required for the initiation and progression of DNA replication. Here we have identified additional eukaryotic AEP-like proteins with DNA-dependent primase and/or polymerase...

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Autors principals: Rudd, Sean G., Glover, Lucy, Jozwiakowski, Stanislaw K., Horn, David, Doherty, Aidan J.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898837/
https://ncbi.nlm.nih.gov/pubmed/24267450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.10.034
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