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Manipulation of the HIF-Vegf pathway rescues methyl tert-butyl ether (MTBE)-induced vascular lesions

Methyl tert-butyl ether (MTBE) has been shown to be specifically anti-angiogenic in piscine and mammalian model systems at concentrations that appear non-toxic in other organ systems. The mechanism by which MTBE targets developing vascular structures is unknown. A global transcriptome analysis of ze...

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Bibliographic Details
Main Authors: Bonventre, Josephine A., Kung, Tiffany S., White, Lori A., Cooper, Keith R.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898687/
https://ncbi.nlm.nih.gov/pubmed/24128854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.10.008
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