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Kv2 dysfunction after peripheral axotomy enhances sensory neuron responsiveness to sustained input()

Peripheral nerve injuries caused by trauma are associated with increased sensory neuron excitability and debilitating chronic pain symptoms. Axotomy-induced alterations in the function of ion channels are thought to largely underlie the pathophysiology of these phenotypes. Here, we characterise the...

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Autors principals: Tsantoulas, Christoforos, Zhu, Lan, Yip, Ping, Grist, John, Michael, Gregory J., McMahon, Stephen B.
Format: Artigo
Idioma:Inglês
Publicat: Academic Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898477/
https://ncbi.nlm.nih.gov/pubmed/24252178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.11.011
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