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The val(158)met COMT polymorphism's effect on atrophy in healthy aging and Parkinson's disease

We investigated whether the val(158)met functional polymorphism of catechol-o-methyltransferase influenced age-related changes in grey matter density and volume, both in healthy individuals (n = 80, ages 18–79) and those with Parkinson's disease (n = 50). Global grey matter volumes and voxelwis...

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Detalles Bibliográficos
Main Authors: Rowe, J.B., Hughes, L., Williams-Gray, C.H., Bishop, S., Fallon, S., Barker, R.A., Owen, A.M.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898476/
https://ncbi.nlm.nih.gov/pubmed/18755526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2008.07.009
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