Neuromedin U receptor 2 knockdown in the paraventricular nucleus modifies behavioral responses to obesogenic high-fat food and leads to increased body weight

Neuromedin U (NMU) is a highly conserved neuropeptide which regulates food intake and body weight. Transgenic mice lacking NMU are hyperphagic and obese, making NMU a novel target for understanding and treating obesity. Neuromedin U receptor 2 (NMUR2) is a high-affinity receptor for NMU found in dis...

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Bibliographic Details
Main Authors: Benzon, Caitlin R., Johnson, Sarah B., McCue, David L., Li, Dingge, Green, Thomas A., Hommel, Jonathan D.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898339/
https://ncbi.nlm.nih.gov/pubmed/24269937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.11.023
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