Haptoglobin (HP) and Haptoglobin-related protein (HPR) copy number variation, natural selection, and trypanosomiasis

Haptoglobin, coded by the HP gene, is a plasma protein that acts as a scavenger for free heme, and haptoglobin-related protein (coded by the HPR gene) forms part of the trypanolytic factor TLF-1, together with apolipoprotein L1 (ApoL1). We analyse the polymorphic small intragenic duplication of the...

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Autors principals: Hardwick, Robert J., Ménard, Anne, Sironi, Manuela, Milet, Jacqueline, Garcia, André, Sese, Claude, Yang, Fengtang, Fu, Beiyuan, Courtin, David, Hollox, Edward J.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2013
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898332/
https://ncbi.nlm.nih.gov/pubmed/24005574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-013-1352-x
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