TREK2 Expressed Selectively in IB4-Binding C-Fiber Nociceptors Hyperpolarizes Their Membrane Potentials and Limits Spontaneous Pain

Ongoing/spontaneous pain behavior is associated with ongoing/spontaneous firing (SF) in adult DRG C-fiber nociceptors (Djouhri et al., 2006). Causes of this SF are not understood. We show here that conducting (sometimes called uninjured) C-nociceptors in neuropathic pain models with more hyperpolari...

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Detalhes bibliográficos
Main Authors: Acosta, Cristian, Djouhri, Laiche, Watkins, Roger, Berry, Carol, Bromage, Kirsty, Lawson, Sally N.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898302/
https://ncbi.nlm.nih.gov/pubmed/24453337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4528-13.2014
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