Absence of systemic toxicity changes following intramuscular administration of novel pSG2.HIVconsv DNA, ChAdV63.HIVconsv and MVA.HIVconsv vaccines to BALB/c mice()

BACKGROUND: The systemic toxicity of three candidate HIV-1 vaccines plasmid pSG2.HIVconsv DNA (D), ChAdV63.HIVconsv (C) and MVA.HIVconsv (M) expressing chimeric immunogen derived from the most conserved regions of the HIV-1 proteome was evaluated in two repeat-dose studies in the male and female BAL...

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Hauptverfasser: Ondondo, Beatrice, Brennan, Caroline, Nicosia, Alfredo, Crome, Steven J., Hanke, Tomáš
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Science 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898262/
https://ncbi.nlm.nih.gov/pubmed/23831324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.06.068
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