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Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro

It has been suggested that clec14a may be involved in tumor angiogenesis. However, a molecular mechanism has not been clearly identified. In this study, we show for the first time that C-type lectin-like domain (CTLD) of clec14a may be important for regulating cell migration and filopodia formation....

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Detalhes bibliográficos
Main Authors: Ki, M K, Jeoung, M H, Choi, J R, Rho, S-S, Kwon, Y-G, Shim, H, Chung, J, Hong, H J, Song, B D, Lee, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898107/
https://ncbi.nlm.nih.gov/pubmed/23644659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.156
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