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Amphotericin B Increases Influenza A Virus Infection by Preventing IFITM3-Mediated Restriction
The IFITMs inhibit influenza A virus (IAV) replication in vitro and in vivo. Here, we establish that the antimycotic heptaen, amphotericin B (AmphoB), prevents IFITM3-mediated restriction of IAV, thereby increasing viral replication. Consistent with its neutralization of IFITM3, a clinical preparati...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898084/ https://ncbi.nlm.nih.gov/pubmed/24268777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.10.033 |
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