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ArchiLD: Hierarchical Visualization of Linkage Disequilibrium in Human Populations

Linkage disequilibrium (LD) is an essential metric for selecting single-nucleotide polymorphisms (SNPs) to use in genetic studies and identifying causal variants from significant tag SNPs. The explosion in the number of polymorphisms that can now be genotyped by commercial arrays makes the interpret...

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Autori principali: Melchiotti, Rossella, Rötzschke, Olaf, Poidinger, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897757/
https://ncbi.nlm.nih.gov/pubmed/24466224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086761
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