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Perturbation of Human Coronary Artery Endothelial Cell Redox State and NADPH Generation by Methylglyoxal

Diabetes is associated with elevated plasma glucose, increased reactive aldehyde formation, oxidative damage, and glycation/glycoxidation of biomolecules. Cellular detoxification of, or protection against, such modifications commonly requires NADPH-dependent reducing equivalents (e.g. GSH). We hypot...

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Detalhes bibliográficos
Main Authors: Morgan, Philip E., Sheahan, Pamela J., Davies, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897751/
https://ncbi.nlm.nih.gov/pubmed/24466151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086564
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