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H-NST Induces LEE Expression and the Formation of Attaching and Effacing Lesions in Enterohemorrhagic Escherichia coli

BACKGROUND: Enteropathogenic E. coli (EPEC) and enterohemorrhagic E. coli are important causes of morbidity and mortality worldwide. These enteric pathogens contain a type III secretion system (T3SS) responsible for the attaching and effacing (A/E) lesion phenotype. The T3SS is encoded by the locus...

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Bibliographic Details
Main Authors: Levine, Jonathan A., Hansen, Anne-Marie, Michalski, Jane M., Hazen, Tracy H., Rasko, David A., Kaper, James B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897749/
https://ncbi.nlm.nih.gov/pubmed/24466172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086618
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