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Reduced Peripheral Expression of the Glucocorticoid Receptor α Isoform in Individuals with Posttraumatic Stress Disorder: A Cumulative Effect of Trauma Burden

BACKGROUND: Posttraumatic stress disorder (PTSD) is a serious psychiatric condition that was found to be associated with altered functioning of the hypothalamic-pituitary-adrenal (HPA) axis and changes in glucocorticoid (GC) responsiveness. The physiological actions of GCs are primarily mediated thr...

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Detalhes bibliográficos
Main Authors: Gola, Hannah, Engler, Andrea, Morath, Julia, Adenauer, Hannah, Elbert, Thomas, Kolassa, Iris-Tatjana, Engler, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897679/
https://ncbi.nlm.nih.gov/pubmed/24466032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086333
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