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Inactivation of Bovine Trypsinogen and Chymotrypsinogen by Diisopropylphosphorofluoridate

Diisopropylphosphorofluoridate reacts with trypsinogen and chymotrypsinogen and inhibits the potential activity of both zymogens. The reactions follow pseudo first-order kinetics and proceed approximately four orders of magnitude slower than diisopropylphosphorylation of the corresponding enzymes. C...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Morgan, Paul H., Robinson, Neal C., Walsh, Kenneth A., Neurath, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389761/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4508324/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.11.3312
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