Oral Delivery of Exenatide via Microspheres Prepared by Cross-Linking of Alginate and Hyaluronate

Exenatide is an FDA-approved glucose-lowering peptide drug for the treatment of type 2 diabetes by subcutaneous injection. To address the issues on the inconvenience for patient use and the difficulty of oral administration of peptide drugs, chemical cross-linking of two pH-responsive biomaterials,...

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Bibliographic Details
Main Authors: Zhang, Baojie, He, Dongyang, Fan, Yu, Liu, Nan, Chen, Yijun
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897602/
https://ncbi.nlm.nih.gov/pubmed/24465870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086064
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