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Generation of Multiple Fluid-Phase C3b:Plasma Protein Complexes During Complement Activation. Possible Implications in C3 Glomerulopathies

The complement system is tightly regulated to safeguard against tissue damage that results from unwanted activation. The key step of C3 cleavage to C3b is regulated by multiple mechanisms that control the initiation and extent of activation. This study demonstrated that C3b:plasma protein complexes...

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Detalhes bibliográficos
Main Authors: Ramadass, Mahalakshmi, Ghebrehiwet, Berhane, Smith, Richard J., Kew, Richard R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897554/
https://ncbi.nlm.nih.gov/pubmed/24367026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302288
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