MSLN Gene Silencing Has an Anti-Malignant Effect on Cell Lines Overexpressing Mesothelin Deriving from Malignant Pleural Mesothelioma

Genes involved in the carcinogenetic mechanisms underlying malignant pleural mesothelioma (MPM) are still poorly characterized. So far, mesothelin (MSLN) has aroused the most interest. It encodes for a membrane glycoprotein, frequently over-expressed in various malignancies such as MPM, and ovarian...

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Autors principals: Melaiu, Ombretta, Stebbing, Justin, Lombardo, Ylenia, Bracci, Elisa, Uehara, Norihisa, Bonotti, Alessandra, Cristaudo, Alfonso, Foddis, Rudy, Mutti, Luciano, Barale, Roberto, Gemignani, Federica, Giamas, Georgios, Landi, Stefano
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897543/
https://ncbi.nlm.nih.gov/pubmed/24465798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085935
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