Resistin disrupts glycogen synthesis under high insulin and high glucose levels by down-regulating the hepatic levels of GSK3β

The effect of mouse resistin on hepatic insulin resistance in vivo and in vitro, and its possible molecular mechanism were examined. Focusing on liver glycogen metabolism and gluconeogenesis, which are important parts of glucose metabolism, in primary cultures of rat hepatocytes we found that glycog...

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Main Authors: Song, Rongjing, Wang, Xi, Mao, Yiqing, Li, Hui, Li, Zhixin, Xu, Wei, Wang, Rong, Guo, Tingting, Jin, Ling, Zhang, Xiaojing, Zhang, Yizhuang, Zhou, Na, Hu, Ruobi, Jia, Jianwei, Lei, Zhen, Irwin, David M., Niu, Gang, Tan, Huanran
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897445/
https://ncbi.nlm.nih.gov/pubmed/23860320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2013.06.085
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