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In Vitro Repair of X-Irradiated DNA Extracted from Bacillus subtilis Deficient in Polymerase I

DNA extracted from x-irradiated cells of a mutant of Bacillus subtilis deficient in DNA polymerase I has greatly reduced biological activity. This DNA, which has many single-strand nicks, can be repaired in vitro with purified DNA polymerase I and DNA ligase or with lysates of wild-type B. subtilis...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Laipis, Philip J., Ganesan, A. T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389738/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4628873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.11.3211
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