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DNA Modification Methylase Activity of Escherichia coli Restriction Endonucleases K and P

The highly purified restriction endonucleases of E. coli K and coliphage P1 transfer methyl groups from S-adenosylmethionine to adenine residues of unmodified DNA. Incubation of unmodified DNA with endonucleases K or P and S-adenosylmethionine renders the DNA resistant to restriction. The enzymes, t...

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Detalles Bibliográficos
Main Authors: Haberman, Allan, Heywood, Janet, Meselson, Matthew
Formato: Artigo
Idioma:Inglês
Publicado: 1972
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC389721/
https://ncbi.nlm.nih.gov/pubmed/4564204
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