IL-23 Is Critical for Induction of Arthritis, Osteoclast Formation, and Maintenance of Bone Mass

The role of IL-23 in the development of arthritis and bone metabolism was studied using systemic IL-23 exposure in adult mice via hydrodynamic delivery of IL-23 minicircle DNA in vivo and in mice genetically deficient in IL-23. Systemic IL-23 exposure induced chronic arthritis, severe bone loss, and...

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Bibliografski detalji
Glavni autori: Adamopoulos, Iannis E., Tessmer, Marlowe, Chao, Cheng-Chi, Adda, Sarvesh, Gorman, Dan, Petro, Mary, Chou, Chuan-Chu, Pierce, Robert H., Yao, Wei, Lane, Nancy E., Laface, Drake, Bowman, Edward P.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896980/
https://ncbi.nlm.nih.gov/pubmed/21670317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003986
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