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Genetic Variation in Nicotine Metabolism Predicts the Efficacy of Extended-Duration Transdermal Nicotine Therapy

In a placebo-controlled trial, we examined the efficacy of a 6-month (“extended”) transdermal nicotine therapy vs. the 8-week (“standard”) therapy in 471 Caucasian smokers with either normal or reduced rates of nicotine metabolism as determined at pretreatment. Extended therapy was superior to stand...

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Autori principali: Lerman, C, Jepson, C, Wileyto, EP, Patterson, F, Schnoll, R, Mroziewicz, M, Benowitz, N, Tyndale, RF
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896974/
https://ncbi.nlm.nih.gov/pubmed/20336063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2010.3
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