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Alteration of the Cytotoxic Action of Sensitized Lymphocytes by Cholinergic Agents and Activators of Adenylate Cyclase

The cytotoxic action of lymphocytes upon cells bearing alloantigens to which they are sensitized is inhibited by agents that elevate intracellular amounts of 3′:5′-cyclic AMP: prostaglandin E(1), cholera toxin, and theophylline. Cholinergic agents, added in the range of 1 to 100 pM, enhance cytotoxi...

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Autors principals: Strom, Terry B., Deisseroth, Albert, Morganroth, Joel, Carpenter, Charles B., Merrill, John P.
Format: Artigo
Idioma:Inglês
Publicat: 1972
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC389693/
https://ncbi.nlm.nih.gov/pubmed/4342971
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