Diabetic uterus environment may play a key role in alterations of DNA methylation of several imprinted genes at mid-gestation in mice

BACKGROUND: Maternal diabetes mellitus not only has severe deleterious effects on fetal development, but also it affects transmission to the next generation. However, the underlying mechanisms for these effects are still not clear. METHODS: We investigated the methylation patterns and expressions of...

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Detalhes bibliográficos
Main Authors: Ge, Zhao-Jia, Liang, Qiu-Xia, Luo, Shi-Ming, Wei, Yan-Chang, Han, Zhi-Ming, Schatten, Heide, Sun, Qing-Yuan, Zhang, Cui-Lian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896855/
https://ncbi.nlm.nih.gov/pubmed/24378208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-11-119
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