Functional and genetic characterization of clinical malignant hyperthermia crises: a multi-centre study

BACKGROUND: Malignant hyperthermia (MH) is a rare pharmacogenetic disorder which is characterized by life-threatening metabolic crises during general anesthesia. Classical triggering substances are volatile anesthetics and succinylcholine (SCh). The molecular basis of MH is excessive release of Ca(2...

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Autors principals: Klingler, Werner, Heiderich, Sebastian, Girard, Thierry, Gravino, Elvira, Heffron, James JA, Johannsen, Stephan, Jurkat-Rott, Karin, Rüffert, Henrik, Schuster, Frank, Snoeck, Marc, Sorrentino, Vincenzo, Tegazzin, Vincenzo, Lehmann-Horn, Frank
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896768/
https://ncbi.nlm.nih.gov/pubmed/24433488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-9-8
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