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Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200

BACKGROUND: The role of exosomes in the pathogenesis and metastatic spread of cancer remains to be fully elucidated. Recent studies support the hypothesis that the release of exosomes from cells modifies local extracellular conditions to promote cell growth and neovascularisation. In addition, exoso...

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Detalhes bibliográficos
Main Authors: Kobayashi, Miharu, Salomon, Carlos, Tapia, Jorge, Illanes, Sebastian E, Mitchell, Murray D, Rice, Gregory E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896684/
https://ncbi.nlm.nih.gov/pubmed/24393345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-4
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