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Similarities Between the Conformation of Arsanilazotyrosine 248 of Carboxypeptidase A(α) in the Crystalline State and in Solution

Modification of carboxypeptidase A(γ) crystals (Anson) with diazotized arsanilic acid specifically labels tyrosine 248; at pH 8.2 the modified enzyme gives yellow crystals, but a red solution. It has been suggested that arsanilazotyrosine 248 forms a complex with the Zn cofactor accounting for the r...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Quiocho, Florante A., Mcmurray, Cecil H., Lipscomb, William N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1972
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389660/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4507609/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.10.2850
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