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Lessons for the clinic from rituximab pharmacokinetics and pharmacodynamics
The anti-CD20 antibody rituximab (RTX; Rituxan®, MabThera®) was the first anti-cancer antibody approved by the US Food and Drug Administration in 1997 and it is now the most-studied unconjugated therapeutic antibody. The knowledge gained over the past 15 y on the pharmacodynamics (PD) of this antibo...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896596/ https://ncbi.nlm.nih.gov/pubmed/23933992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.26008 |
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