Llwytho...

Natural and glucosyl flavonoids inhibit poly(ADP-ribose) polymerase activity and induce synthetic lethality in BRCA mutant cells

Poly(ADP-ribose) polymerase (PARP) inhibitors have been proven to represent superior clinical agents targeting DNA repair mechanisms in cancer therapy. We investigated PARP inhibitory effects of the natural and synthetic flavonoids (quercetin, rutin, monoglucosyl rutin and maltooligosyl rutin) and t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: MAEDA, JUNKO, ROYBAL, ERICA J., BRENTS, COLLEEN A., UESAKA, MITSURU, AIZAWA, YASUSHI, KATO, TAKAMITSU A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896521/
https://ncbi.nlm.nih.gov/pubmed/24317580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2013.2902
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!