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Pro-Inflammatory Mediators and Apoptosis Correlate to rt-PA Response in a Novel Mouse Model of Thromboembolic Stroke

BACKGROUND: A recent study suggests that patients with persistent occlusion of the middle cerebral artery (MCA) following treatment with recombinant tissue plasminogen activator (rt-PA) have better outcomes than patients with MCA occlusion not receiving rt-PA. We performed a study to elucidate possi...

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Autors principals: Ansar, Saema, Chatzikonstantinou, Eva, Thiagarajah, Rushani, Tritschler, Laurent, Fatar, Marc, Hennerici, Michael G., Meairs, Stephen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896417/
https://ncbi.nlm.nih.gov/pubmed/24465746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085849
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