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Synthesis of novel derivatives of 5-hydroxymethylcytosine and 5-formylcytosine as tools for epigenetics

In this work we present for the first time the synthesis of novel 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) derivatives that can be used as tools in the emerging field of epigenetics for deciphering chemical biology of TET-mediated processes.

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Hlavní autoři: Chentsova, Anna, Kapourani, Era, Giannis, Athanassios
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896258/
https://ncbi.nlm.nih.gov/pubmed/24454558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.2
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